Sodium ya Heparin CAS 9041-08-1

Sodium ya Heparin ni imiti igabanya ubukana, ikaba ari mucopolysaccharide.Numunyu wa sodium wa glucosamine sulfate yakuwe mumitsi yo munda yingurube, inka nintama.hagati.Sodium ya Heparin ifite imirimo yo gukumira ikwirakwizwa rya platine no kurimbuka, ikabuza ihinduka rya fibrinogen muri fibrin monomer, ikabuza gukora tromboplastine no kurwanya tromboplastine, ikarinda ihinduka rya prothrombine muri trombine na antithrombine.

Sodium ya Heparin irashobora gutinza cyangwa kurinda amaraso haba muri vitro ndetse no muri vivo.Uburyo bwibikorwa byabwo biragoye cyane kandi bigira ingaruka kumahuriro menshi mugikorwa cya coagulation.Inshingano zayo ni: ①Buza imiterere n'imikorere ya tromboplastine, bityo wirinde prothrombine kuba trombine;②Mu kwibanda cyane, irashobora kubuza trombine nizindi mpamvu ziterwa na coagulation, ikabuza fibrinogen kuba Protein ya fibrin;③ irashobora gukumira kwegeranya no gusenya platine.Byongeye kandi, ingaruka za anticoagulant ya sodium heparin iracyafite isano na sulfate ikabije ya molekile yayo.Ibintu bya alkaline byashizwemo neza nka protamine cyangwa ubururu bwa toluidine birashobora kugabanya ingaruka mbi zabyo, bityo birashobora kubuza anticoagulant.coagulation.Kubera ko heparin ishobora gukora kandi ikarekura lipase ya lipoproteine ​​mu mubiri, hydrolyze triglyceride na lipoprotein nkeya ya chylomicrons, bityo ikagira n'ingaruka za hypolipidemic.

Sodium ya Heparin irashobora gukoreshwa mu kuvura indwara ikaze ya tromboembolique, ikwirakwiza imitsi y'amaraso (DIC).Mu myaka yashize, heparin byagaragaye ko ifite ingaruka zo gukuraho lipide yamaraso.Gutera imitsi cyangwa inshinge zimbitse (cyangwa inshinge zo munsi), 5.000 kugeza 10,000.Sodium ya Heparin ntabwo ifite uburozi kandi guhita biva amaraso ni byo byago byingenzi byo kunywa cyane heparin.Bidafite akamaro mu kanwa, bigomba gutangwa no gutera inshinge.Gutera inshinge cyangwa gutera inshinge zirakaze cyane, rimwe na rimwe ingaruka ziterwa na allergique, ndetse no kunywa birenze urugero bishobora no gutera umutima;rimwe na rimwe guta umusatsi byigihe gito no gucibwamo.Byongeye kandi, irashobora gutera kuvunika bidatinze.Gukoresha igihe kirekire birashobora rimwe na rimwe gutera trombose, bishobora kuba ingaruka zo kugabanuka kwa anticoagulase-III.Sodium ya Heparin yandujwe ku barwayi bafite ikibazo cyo kuva amaraso, umwijima ukabije no kubura impyiko, hypertension ikabije, hemophilia, kuva amaraso ava mu nda, ibisebe bya peptike, abagore batwite na nyuma yo kubyara, ibibyimba byo mu nda, ihahamuka no kubagwa.